BDBM8698 3-(dimethylamino)-N-{4-[(1E)-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]hydrazin-1-ylidene}methyl]phenyl}propanamide::pyrazolopyrimidine derivative 50

SMILES COc1cccc(c1)-n1ncc2c(N=NCc3ccc(NC(=O)CCN(C)C)cc3)ncnc12

InChI Key InChIKey=AYSBYBIYAXHXRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8698   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8698(3-(dimethylamino)-N-{4-[(1E)-{2-[1-(3-methoxypheny...)
Affinity DataIC50: 5.01nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2006
Entry Details Article
PubMed