BDBM86733 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE::CAS_6508-43-6::CHEMBL491762::L-152,804

SMILES CC1(C)CC(=O)C(C2C3=C(CC(C)(C)CC3=O)Oc3ccccc23)C(=O)C1

InChI Key InChIKey=XQDXIHYKAGHZRX-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 86733   

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neuropeptide Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neuropeptide Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(CAS_6508-43-6 | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed