BDBM8656 4-[(1E)-(2-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}hydrazin-1-ylidene)methyl]pyridine::pyrazolopyrimidine derivative 8

SMILES C(N=Nc1ncnc2n(ncc12)-c1ccccc1)c1ccncc1

InChI Key InChIKey=WMFAQTOAOLDBKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8656   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8656(4-[(1E)-(2-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed