BDBM86544 CAS_192231-16-6::CHEMBL111580::NSC_6442277::SIB-1508Y

SMILES CN1CCCC1c1cncc(c1)C#C

InChI Key InChIKey=NUPUDYKEEJNZRG-UHFFFAOYSA-N

Data  3 KI  1 IC50  11 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 86544   

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataIC50: 1.01E+4nMAssay Description:Muscarinic acetylcholine receptor binding (rat cortical membranes) was determined by displacement of [3H]quinuclidinyl benzylate [3H]QNB)More data for this Ligand-Target Pair

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Date in BDB:
11/1/2012
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TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  5.20E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair

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11/1/2012
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TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  5.30E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair

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TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  1.50E+4nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  1.50E+4nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  2.60E+3nMAssay Description:Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair

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Date in BDB:
11/5/2012
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TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  4.10E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  4.10E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  2.60E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  2.60E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  2.30E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
Sibia Neurosciences

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataEC50:  2.50E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair

Target InfoPDB
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TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Targacept

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair

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Date in BDB:
5/31/2012
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TargetNeuronal acetylcholine receptor subunit alpha-5(Rat)
Targacept

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataKi:  991nMMore data for this Ligand-Target Pair

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TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Targacept

Curated by PDSP K_i Database

LigandBDBM86544(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

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Date in BDB:
5/31/2012
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