BDBM86234 CAS_64057-70-1::MDMA,S(+)::NSC_126235

SMILES CN[C@H](C)Cc1ccc2OCOc2c1

InChI Key InChIKey=SHXWCVYOXRDMCX-UHFFFAOYSA-N

Data  7 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86234   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataIC50: 1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataEC50:  7.40E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataEC50:  3.70E+3nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataEC50:  340nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  74nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetNorepinephrine transporter(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  136nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  142nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  630nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  3.31E+3nMAssay Description:Displacement of [3H]DOB from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat cortex, striatum and cerebellum-dissected brain after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed