BDBM86029 trans-H2-PAT(+)

SMILES CN(C)[C@@H]1C[C@@H](c2ccccc2)c2ccccc2C1

InChI Key InChIKey=DXJUCAUQIHNOAF-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 86029   

TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataIC50: 0.525nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataIC50: 0.520nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
University of North Carolina At Chapel Hill

Curated by PDSP Ki Database
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  11.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
University of North Carolina At Chapel Hill

Curated by PDSP Ki Database
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of North Carolina At Chapel Hill

Curated by PDSP Ki Database
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  29.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  30nMAssay Description:Binding affinity to human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of North Carolina At Chapel Hill

Curated by PDSP Ki Database
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  42.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  240nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  430nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2C-INI receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86029(trans-H2-PAT(+))
Affinity DataKi:  470nMAssay Description:Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed