BDBM86010 Chalcone, 10

SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccccc1

InChI Key InChIKey=GVKYSLWFMZCXBQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86010   

TargetAcetylcholinesterase(Pacific electric ray)
Quaid-I-Azam University

LigandPNGBDBM86010(Chalcone, 10)
Affinity DataIC50: 3.92E+4nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM86010(Chalcone, 10)
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as reduction in DHT-induced transcriptional activation after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM86010(Chalcone, 10)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetArachidonate 12-lipoxygenase, 12R-type(Human)
Quaid-I-Azam University

LigandPNGBDBM86010(Chalcone, 10)
Affinity DataKi:  5.76E+4nM ΔG°:  -5.78kcal/molepH: 8.0 T: 2°CAssay Description:In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2012
Entry Details Article
PubMed