BDBM86007 Chalcone, 6

SMILES Oc1ccccc1C(=O)\C=C\c1ccccc1

InChI Key InChIKey=AETKQQBRKSELEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86007   

TargetAcetylcholinesterase(Pacific electric ray)
Quaid-I-Azam University

LigandPNGBDBM86007(Chalcone, 6)
Affinity DataIC50: 5.92E+4nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86007(Chalcone, 6)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM86007(Chalcone, 6)
Affinity DataIC50: 7.13E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetTubulin alpha chain(Sheep)TBA
LigandPNGBDBM86007(Chalcone, 6)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article