BDBM86005 Chalcone, 4

SMILES COc1ccc(\C=C\C(=O)c2ccccc2)cc1

InChI Key InChIKey=XUFXKBJMCRJATM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86005   

TargetCarboxylic ester hydrolase(Horse)
Quaid-I-Azam University

LigandPNGBDBM86005(Chalcone, 4)
Affinity DataIC50: 3.90E+4nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM86005(Chalcone, 4)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
LigandPNGBDBM86005(Chalcone, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article