BDBM85444 CHEMBL506025::Isotetrandrine (R,S)::Pheanthine (R,R)

SMILES COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34

InChI Key InChIKey=WVTKBKWTSCPRNU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 85444   

TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Pheanthine (R,R) | Isotetrandrine (...)
Affinity DataIC50: 1.22E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2012
Entry Details Article
PubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Pheanthine (R,R) | Isotetrandrine (...)
Affinity DataIC50: 2.35E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM85444(CHEMBL506025 | Pheanthine (R,R) | Isotetrandrine (...)
Affinity DataIC50: 3.33E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM85444(CHEMBL506025 | Pheanthine (R,R) | Isotetrandrine (...)
Affinity DataIC50: 670nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed