BDBM85428 NEP inhibitor, 6h

SMILES OC(=O)c1cncc(NC(=O)C(CS)Cc2ccccc2)c1

InChI Key InChIKey=IYTTWDDEBZRBIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85428   

TargetNeprilysin(Rat)
R & D, Zambon Group

LigandPNGBDBM85428(NEP inhibitor, 6h)
Affinity DataIC50: 5nMT: 2°CAssay Description:Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2012
Entry Details Article
PubMed