BDBM8537 4-[(1E)-{2-[7-(3-methoxyphenyl)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazin-1-ylidene}methyl]pyridine::heterocyclic pyrimidyl hydrazone 3

SMILES COc1cccc(c1)-c1cn(C)c2c(N=NCc3ccncc3)ncnc12

InChI Key InChIKey=ZKXPQZDDINKFGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8537   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8537(4-[(1E)-{2-[7-(3-methoxyphenyl)-5-methyl-5H-pyrrol...)
Affinity DataIC50: 501nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed