BDBM85198 CAS_127096::Hydroxynefazodone::NSC_127096

SMILES CC(O)c1nn(CCCN2CCN(CC2)c2ccc(Cl)cc2)c(=O)n1CCOc1ccccc1

InChI Key InChIKey=PPJRQXMDFSRWFH-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 85198   

Target5-hydroxytryptamine receptor 2A(Rat)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  7.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetHistamine H1 receptor(Guinea pig)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  56nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  63nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  612nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  664nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  728nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  1.02E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  1.05E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM85198(NSC_127096 | CAS_127096 | Hydroxynefazodone)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details
PubMed