BDBM85126 Thr1 inhibitor, 6

SMILES CC1NN(c2nc(cc(O)c12)C(F)(F)F)c1ccccc1

InChI Key InChIKey=BRNIETYMZWARTR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85126   

TargetHomoserine kinase(Escherichia coli (strain K12))
Mcmaster University

LigandPNGBDBM85126(Thr1 inhibitor, 6)
Affinity DataKi:  8.60E+3nM ΔG°:  -7.18kcal/molepH: 7.5 T: 2°CAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed