BDBM85117 Cyclophilin Inhibitor, 3c

SMILES COC(=O)[C@H](CCCN=C(N)NN(=O)=O)C1C(=O)CC2C1=CC(=O)CC2(C)C

InChI Key InChIKey=WLLXUSAXZPDCPL-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85117   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)
Affinity DataKd:  3.19E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)
Affinity DataKd:  2.96E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)
Affinity DataKi: >1.00E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed