BDBM85067 CAS_170856-41-4::CHEMBL81330::PNU 96415E::PNU-96415E

SMILES Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1

InChI Key InChIKey=UKOCGOXTVCIACM-UHFFFAOYSA-N

Data  25 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 85067   

TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-nemonapride from human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  3nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  3nMAssay Description:Binding affinity of [3H]spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Pharmacia & Upjohn

Curated by PDSP Ki Database
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  5.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of serotonin 5-HT2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  38nMAssay Description:Inhibition of alpha1 adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by PDSP Ki Database
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  69.6nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  120nMAssay Description:Binding affinity of [3H]-8-OH-DPAT towards 5-hydroxytryptamine 1A receptor in cloned mammalian receptor expressed in cultured cells or from rat whole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  134nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  134nMAssay Description:Inhibition of serotonin 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  160nMAssay Description:Binding affinity of [3H]U-86170 towards Dopamine receptor D2 in cloned mammalian receptor expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  181nMAssay Description:Inhibition of alpha2 adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by PDSP Ki Database
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  181nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  199nMAssay Description:Binding affinity to human D2R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  199nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  199nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  240nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  240nMAssay Description:Binding affinity of [3H]spiperone towards Dopamine receptor D3 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  410nMAssay Description:Binding affinity of [3H]SCH-23,390 towards Dopamine receptor D1 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  411nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  411nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Pharmacia & Upjohn

Curated by PDSP Ki Database
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  678nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed