BDBM85066 Luzindole,5-Methoxy

SMILES COc1ccc2[nH]c(Cc3ccccc3)c(CCNC(C)=O)c2c1

InChI Key InChIKey=MUQOTEHRXIKHKR-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 85066   

TargetMelatonin receptor(Rabbit)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  0.25nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT2 receptor expressed in COS7 cells incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMelatonin receptor(Rabbit)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor(Rabbit)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  32.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  32.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM85066(Luzindole,5-Methoxy)
Affinity DataKi:  33nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT1 receptor expressed in COS7 cells incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed