BDBM84847 1-azolyl-4-phenyl-2-butanone, 49a::CHEMBL558183

SMILES C(CC1(Cn2ccnc2)OCCO1)c1ccccc1

InChI Key InChIKey=GKXREDWUTLNBPG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 84847   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 700nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2020
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM84847(CHEMBL558183 | 1-azolyl-4-phenyl-2-butanone, 49a)
Affinity DataIC50: 700nMAssay Description:Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2020
Entry Details Article
PubMed