BDBM84684 1-Subsituted 1H-imidazole, 21::CHEMBL543494

SMILES OC(=O)CCCCn1ccnc1

InChI Key InChIKey=YTRRZWTXQVETAL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 84684   

TargetCytochrome P450 2A6(Human)
University of Basel

LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 1.78E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A13(Human)
University of Basel

LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 8.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Thromboxane synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed