BDBM84611 2-methyl-N-pyridin-4-yl-benzamide, 2a

SMILES Cc1ccccc1C(=O)Nc1ccncc1

InChI Key InChIKey=IPNZONAZPKLNST-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84611   

TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84611(2-methyl-N-pyridin-4-yl-benzamide, 2a)
Affinity DataIC50: 8.00E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM84611(2-methyl-N-pyridin-4-yl-benzamide, 2a)
Affinity DataKi: >3.50E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM84611(2-methyl-N-pyridin-4-yl-benzamide, 2a)
Affinity DataKi: >3.50E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed