BDBM84581 Thioxothiazolidinone derivative, 1

SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(Cl)c2)cc(c1O)N(=O)=O

InChI Key InChIKey=PVXVYUCGACTAGE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 84581   

LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 4.30E+3nMpH: 6.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Mcgill University

LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 5.00E+4nMpH: 6.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Mcgill University

LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 5.00E+4nMpH: 6.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 4.10E+3nMpH: 7.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 5.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 3.90E+3nMpH: 7.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 3.70E+3nMpH: 7.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 9.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed