BDBM84534 Indirubin derivative, 20

SMILES OS(=O)(=O)c1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1

InChI Key InChIKey=IHBOEHLUIBMBMY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 84534   

TargetCyclin-dependent kinase 2(Human)
Schering

LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 500nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Schering

LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 300nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Schering

LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetKit ligand(Human)
Schering

LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
LigandPNGBDBM84534(Indirubin derivative, 20)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed