BDBM84516 Sulindac analogue, 13

SMILES CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccsc1

InChI Key InChIKey=JJOHZCUOKLOYMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84516   

TargetVascular endothelial growth factor receptor 2(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84516(Sulindac analogue, 13)
Affinity DataIC50: 1.40E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84516(Sulindac analogue, 13)
Affinity DataIC50: 1.50E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84516(Sulindac analogue, 13)
Affinity DataIC50: 600nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed