BDBM84495 CHEMBL1945189::Roseophilin, 1

SMILES COc1cc(oc1C1=c2[nH]c3=CCCCCCCC[C@@H]1[C@@H](C(C)C)c2c3)-c1[nH]ccc1Cl

InChI Key InChIKey=ZRVCZOMHUMDGIN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 84495   

TargetM-phase inducer phosphatase 1(Human)
Max-Planck-Institut FÜR Kohlenforschung

LigandPNGBDBM84495(CHEMBL1945189 | Roseophilin, 1)
Affinity DataIC50: 2.80E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme concentrations were chose to yield absorption changes of 0.2 OD at 405 nm within 80 min for 4-nitrophenyl phosphate (pNPP) in the absence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max-Planck-Institut FÜR Kohlenforschung

LigandPNGBDBM84495(CHEMBL1945189 | Roseophilin, 1)
Affinity DataIC50: 3.80E+4nMpH: 7.2 T: 2°CAssay Description:Enzyme concentrations were chose to yield absorption changes of 0.2 OD at 405 nm within 80 min for 4-nitrophenyl phosphate (pNPP) in the absence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Max-Planck-Institut FÜR Kohlenforschung

LigandPNGBDBM84495(CHEMBL1945189 | Roseophilin, 1)
Affinity DataIC50: 3.20E+4nMpH: 6.5 T: 2°CAssay Description:Enzyme concentrations were chose to yield absorption changes of 0.2 OD at 405 nm within 80 min for 4-nitrophenyl phosphate (pNPP) in the absence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM84495(CHEMBL1945189 | Roseophilin, 1)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed