BDBM8447 2-[(5Z)-5-[(5-{[(5Z)-3-(carboxymethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}thiophen-2-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid::ChemBiolDrugDes71131 Compound 67::Rhodanine-thiophene analogue 12

SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(\C=C3/SC(=S)N(CC(O)=O)C3=O)s2)C1=O

InChI Key InChIKey=YWMLTQGMYQMDLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8447   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8447(ChemBiolDrugDes71131 Compound 67 | 2-[(5Z)-5-[(5-{...)
Affinity DataIC50: 1.60E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2006
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8447(ChemBiolDrugDes71131 Compound 67 | 2-[(5Z)-5-[(5-{...)
Affinity DataIC50: 320nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed