BDBM84450 Isoindoline, 17

SMILES OCC(CN1Cc2ccc(cc2C1)C(F)(F)F)N1CCC(CC1)c1noc2cc(F)ccc12

InChI Key InChIKey=QRWILOLSJSALOC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84450   

TargetD(4) dopamine receptor(Human)
Aventis Pharmaceuticals

LigandPNGBDBM84450(Isoindoline, 17)
Affinity DataKi:  19.1nMAssay Description:Dopamine D4.2 and D2S receptor binding was performed at NPS Allexlix Corp.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Aventis Pharmaceuticals

LigandPNGBDBM84450(Isoindoline, 17)
Affinity DataKi:  26nMAssay Description:All rat alpha-1 adrenoceptor binding was performed by Hugo M. vargas, Karen M. Brooks and Lynn Laws-Ricker.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Aventis Pharmaceuticals

LigandPNGBDBM84450(Isoindoline, 17)
Affinity DataKi:  501nMAssay Description:Dopamine D4.2 and D2S receptor binding was performed at NPS Allexlix Corp.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2012
Entry Details Article
PubMed