BDBM8377 N-[6-(6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-3-yl]cyclopropanecarboxamide::indazole analogue 19

SMILES O=C(Nc1n[nH]c2cc(ccc12)-c1ccc(=O)[nH]c1)C1CC1

InChI Key InChIKey=MNNYKYHFLQMZJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8377   

TargetGlycogen synthase kinase-3 alpha(Human)
Glaxosmithkline

LigandPNGBDBM8377(N-[6-(6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-3-...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8377(N-[6-(6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2006
Entry Details Article
PubMed