BDBM83393 6-(4-morpholinyl)-4,4-diphenyl-3-hexanone::6-morpholin-4-yl-4,4-diphenyl-hexan-3-one::6-morpholin-4-yl-4,4-diphenylhexan-3-one::6-morpholino-4,4-diphenyl-hexan-3-one::MLS001143358::SMR000473193::cid_44686

SMILES O=C(CCn1cnc2c([nH]c3ccc(C(F)(F)F)cc32)c1=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1

InChI Key InChIKey=SXKOCXTXIUNMEN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83393   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83393BDBM83393(3-(3-oxo-3-(4-(3-(trifluoromethyl)phenyl)piperazin...)
Affinity DataEC50:  1.03E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent