BDBM83358 4-(phenylmethyl)-1-[[1-(2-thiazolyl)-2-pyrrolyl]methyl]-4-piperidinecarboxylic acid ethyl ester::4-benzyl-1-[(1-thiazol-2-ylpyrrol-2-yl)methyl]isonipecotic acid ethyl ester::MLS000733812::SMR000316747::cid_16191792::ethyl 4-(phenylmethyl)-1-[[1-(1,3-thiazol-2-yl)pyrrol-2-yl]methyl]piperidine-4-carboxylate::ethyl 4-benzyl-1-[[1-(1,3-thiazol-2-yl)pyrrol-2-yl]methyl]piperidine-4-carboxylate::ethyl 4-benzyl-1-{[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methyl}piperidine-4-carboxylate

SMILES Cc1c(O)cc(F)c(C)c1-n1c(N)c(C(N)=O)c2cnc(C3CC3)c(F)c21

InChI Key InChIKey=WEUCOGAOZHFURB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83358   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83358BDBM83358(US20250388583, Compound 623)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent