BDBM83336 1-[(5-methyl-2-thienyl)methyl]-4-(2-phenoxyethyl)isonipecotic acid ethyl ester::1-[(5-methyl-2-thiophenyl)methyl]-4-(2-phenoxyethyl)-4-piperidinecarboxylic acid ethyl ester::MLS000735095::SMR000319407::cid_16188315::ethyl 1-[(5-methyl-2-thienyl)methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate::ethyl 1-[(5-methylthiophen-2-yl)methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)cc(F)c(O)c3C)c2nc1C

InChI Key InChIKey=KTCKKCPJMYCGME-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83336   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83336BDBM83336(US20250388583, Compound 594)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent