BDBM83332 1-[(2-methyl-5-thiazolyl)methyl]-4-(2-phenoxyethyl)-4-piperidinecarboxylic acid ethyl ester::1-[(2-methylthiazol-5-yl)methyl]-4-(2-phenoxyethyl)isonipecotic acid ethyl ester::MLS000735366::SMR000319337::cid_16187535::ethyl 1-[(2-methyl-1,3-thiazol-5-yl)methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2cnc(NCCO)nc21

InChI Key InChIKey=AQDWISRSCBMKHV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83332   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83332BDBM83332(US20250388583, Compound 588)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent