BDBM8325 N-{5-phenyl-1H-pyrazolo[4,3-d]pyrimidin-3-yl}butanamide::pyrazolopyrimidine deriv. 7

SMILES CCCC(=O)Nc1[nH]nc2cnc(nc12)-c1ccccc1

InChI Key InChIKey=OLQOBGISDJZONR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8325   

TargetGlycogen synthase kinase-3 alpha(Human)
Glaxosmithkline

LigandPNGBDBM8325(N-{5-phenyl-1H-pyrazolo[4,3-d]pyrimidin-3-yl}butan...)
Affinity DataIC50: 2.70E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM8325(N-{5-phenyl-1H-pyrazolo[4,3-d]pyrimidin-3-yl}butan...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed