BDBM8295 3-(4-chlorophenyl)-4-[(3,5-dichloro-4-hydroxyphenyl)amino]-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 9c

SMILES CN1C(=O)C(Nc2cc(Cl)c(O)c(Cl)c2)=C(C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=WKXYCFKOVOUTSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8295   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8295(3-(4-chlorophenyl)-4-[(3,5-dichloro-4-hydroxypheny...)
Affinity DataIC50: 3.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed