BDBM8294 2-chloro-5-{[4-(4-chlorophenyl)-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]amino}benzoic acid::4-arylmaleimide deriv. 9b

SMILES CN1C(=O)C(Nc2ccc(Cl)c(c2)C(O)=O)=C(C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=BDNWHNUISAMQPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8294   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8294(2-chloro-5-{[4-(4-chlorophenyl)-1-methyl-2,5-dioxo...)
Affinity DataIC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed