BDBM8283 3-(3-methoxyphenyl)-4-[methyl(phenyl)amino]-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 7b

SMILES COc1cccc(c1)C1=C(N(C)c2ccccc2)C(=O)NC1=O

InChI Key InChIKey=YLYMSLPKAIYQBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8283   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8283(3-(3-methoxyphenyl)-4-[methyl(phenyl)amino]-2,5-di...)
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed