BDBM8259 3-[(2,5-dioxo-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)amino]benzoic acid::4-arylmaleimide deriv. 6-p

SMILES OC(=O)c1cccc(NC2=C(C(=O)NC2=O)c2ccccc2)c1

InChI Key InChIKey=BOKIQWSDLBGRGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8259   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8259(3-[(2,5-dioxo-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)...)
Affinity DataIC50: 291nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM8259(3-[(2,5-dioxo-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)...)
Affinity DataIC50: 291nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed