BDBM8252 3-[(3,5-dichloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6-i

SMILES Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c2ccccc2N(=O)=O)cc1Cl

InChI Key InChIKey=IYVZGXAXYHRGQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8252   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8252(3-[(3,5-dichloro-4-hydroxyphenyl)amino]-4-(2-nitro...)
Affinity DataIC50: 52nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed