BDBM82390 CCK antagonist synthetic 6

SMILES Clc1ccc2NC(=O)[C@H](Cc3c[nH]c4ccccc34)N=C(c3ccccc3)c2c1

InChI Key InChIKey=OAAIQFQHSUFGKD-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 82390   

TargetCholecystokinin receptor type A(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM82390(CCK antagonist synthetic 6)
Affinity DataIC50: 1.00E+5nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to guinea pig brain(cortex) cholecystokinin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM82390(CCK antagonist synthetic 6)
Affinity DataIC50: 7.00E+4nMAssay Description:Half-maximal inhibition of binding of [125I]gastrin to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM82390(CCK antagonist synthetic 6)
Affinity DataIC50: 3.20E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-33 binding to rat pancreas cholecystokinin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82390(CCK antagonist synthetic 6)
Affinity DataKi:  5.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMed
TargetCholecystokinin(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82390(CCK antagonist synthetic 6)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMed