BDBM82353 1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1 H-indole, 4b

SMILES Fc1ccccc1N1CCN(CCCn2ccc3ccccc23)CC1

InChI Key InChIKey=OCUNZTRMTHXIHS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82353   

TargetSigma intracellular receptor 2(Rat)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82353(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Yeditepe University

LigandPNGBDBM82353(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  264nM ΔG°:  -9.33kcal/molepH: 7.4 T: 2°CAssay Description:The test was performed with the radioligand [3H]-(+)-pentazocine (42.5 Ci/mmol) from Perkin Elmer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM82353(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity to sigma-1 opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed