BDBM8231 3-[(3-chlorophenyl)amino]-4-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6n

SMILES COc1ccc(cc1)C1=C(Nc2cccc(Cl)c2)C(=O)NC1=O

InChI Key InChIKey=ANHNZYQVWLXJET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8231   

TargetGlycogen synthase kinase-3 alpha(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8231(3-[(3-chlorophenyl)amino]-4-(4-methoxyphenyl)-2,5-...)
Affinity DataIC50: 156nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM8231(3-[(3-chlorophenyl)amino]-4-(4-methoxyphenyl)-2,5-...)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed