BDBM82182 3-[2-(4-{[3-(2-fluoroethoxy)-2-methoxyphenyl](hydroxy)methyl}piperidin-1-yl)ethyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one, 4c

SMILES COc1c(OCCF)cccc1C(O)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1

InChI Key InChIKey=IHAGUWFMZBEABU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 82182   

Target5-hydroxytryptamine receptor 2A(Human)
University of Mainz

LigandPNGBDBM82182(3-[2-(4-{[3-(2-fluoroethoxy)-2-methoxyphenyl](hydr...)
Affinity DataKi:  356nM ΔG°:  -9.14kcal/molepH: 7.4 T: 2°CAssay Description:5-HT-2A receptor affinity was determined by a radioligand competition binding assay with GF-62 cells, a clonal cell line expressing high amounts of 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed