BDBM82181 3-(2-{4-[(2,3-dimethoxyphenyl)(hydroxy)methyl]piperidin-1-yl}ethyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one, 4b

SMILES COc1cccc(C(O)C2CCN(CCn3c(=S)[nH]c4ccccc4c3=O)CC2)c1OC

InChI Key InChIKey=YZXZOBPBSBDUBS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 82181   

Target5-hydroxytryptamine receptor 2A(Human)
University of Mainz

LigandPNGBDBM82181(3-(2-{4-[(2,3-dimethoxyphenyl)(hydroxy)methyl]pipe...)
Affinity DataKi:  390nM ΔG°:  -9.09kcal/molepH: 7.4 T: 2°CAssay Description:5-HT-2A receptor affinity was determined by a radioligand competition binding assay with GF-62 cells, a clonal cell line expressing high amounts of 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed