BDBM82164 6-substituted pyrazoloquinolone, 23

SMILES OC(=O)c1cc2nc3cc(Cl)ccc3c(=O)n2[nH]1

InChI Key InChIKey=BMEWCFBPZUQFNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82164   

TargetPhosphopantetheine adenylyltransferase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM82164(6-substituted pyrazoloquinolone, 23)
Affinity DataIC50: 4.90E+4nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2011
Entry Details Article
PubMed
TargetPhosphopantetheine adenylyltransferase(Enterococcus faecalis (strain ATCC 700802 / V583))
Pfizer

LigandPNGBDBM82164(6-substituted pyrazoloquinolone, 23)
Affinity DataIC50: 2.12E+5nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2011
Entry Details Article
PubMed
TargetPhosphopantetheine adenylyltransferase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM82164(6-substituted pyrazoloquinolone, 23)
Affinity DataIC50: 9.30E+4nMAssay Description:The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2011
Entry Details Article
PubMed