BDBM82068 CHEMBL9732::Nicotine-D salicylate::Nicotine-L salicylate

SMILES CN1CCC[C@@H]1c1cccnc1

InChI Key InChIKey=SNICXCGAKADSCV-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 82068   

TargetCytochrome P450 2A6(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A5(Mouse)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha 5 subunit(House fly)
Gifu University

Curated by ChEMBL
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataIC50: 4.22E+5nMAssay Description:Displacement of [3HIMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membranes incubated for 60 min by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataKi:  38nMAssay Description:Inhibition of [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataKi:  87nMAssay Description:In vitro inhibition of [3H]-Cytisine binding in rat brain tissue at Nicotinic acetylcholine receptor alpha4-beta2 at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(Nicotine-D salicylate | CHEMBL9732 | Nicotine-L sa...)
Affinity DataKi:  145nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed