BDBM82055 3-DEAZAADENOSINE::9-Deazaado::Adenosine receptor agonist, 6::CAS_6736-58-9

SMILES Nc1nccc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=DBZQFUNLCALWDY-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 82055   

TargetAdenosylhomocysteinase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of SAH hydrolase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Uppsala University

LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  461nMAssay Description:Radioligand binding assays were performed using membranes prepared from CHO (hA1AR or hA3AR) or HEK293 (hA2AAR) cells stably expressing a single hAR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  2.15E+4nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  5.98E+4nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  6.17E+4nMAssay Description:Binding affinity determined by displacement of specific binding of [125I]N-(4-amino-3-iodophenethyl)-adenosine in membranes of CHO cells stably trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  3.60E+5nMAssay Description:Binding affinity against calf intestine adenosine deaminase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM82055(CAS_6736-58-9 | 3-DEAZAADENOSINE | 9-Deazaado | Ad...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of calf intestinal adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed