BDBM82010 1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine::8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CHEMBL27155

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(O)cc1

InChI Key InChIKey=GLDYYZLOHBXJBU-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 82010   

TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  0.630nMAssay Description:Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]cyclohexyladenosine (CHA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  2.90nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Antagonism of cyclic [3H]AMP accumulation elicited by 15 uM 2-chloroadenosine in [3H]adenine-labeled guinea pig cerebral cortical slices at A2 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  61nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMed