BDBM81987 CHEMBL116048::McN-5652-15

SMILES CSc1ccc(cc1)C1CN2CCCC2c2ccccc12

InChI Key InChIKey=YVKDUIAAPBKHMJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 81987   

TargetSodium-dependent serotonin transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  0.0100nMAssay Description:In vitro binding affinity against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  1.82nMAssay Description:Compound was tested for inhibiting reuptake of [3H]- NE by norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Mcneil Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  2.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
Mcneil Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  3.29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  11.3nMAssay Description:In vitro binding affinity against monoamine transporter NET (norepinephrine transporter) in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  23.5nMAssay Description:Concentration inhibiting Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Mcneil Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  69.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)
Affinity DataKi:  112nMAssay Description:In vitro binding affinity against Dopamine transporter in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed