BDBM81452 CAS_91533::Dimethindene::NSC_91533

SMILES CC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1

InChI Key InChIKey=MVMQESMQSYOVGV-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 81452   

TargetHistamine H1 receptor(Human)
Johannes Gutenberg-University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  0.692nMAssay Description:Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
In Depth
Date in BDB:
9/24/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  45nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  191nMAssay Description:Affinity for Muscarinic acetylcholine receptor M3 expressed in CHO cells by [3H]-NMS displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  263nMAssay Description:Affinity for Muscarinic acetylcholine receptor M1 expressed in CHO cells by [3H]NMS displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  407nMAssay Description:Affinity for Muscarinic acetylcholine receptor M4 expressed in CHO cells by [3H]NMS displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi:  794nMAssay Description:Affinity for Muscarinic acetylcholine receptor M5 expressed in CHO cells by [3H]NMS displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details Article
PubMed
LigandPNGBDBM81452(NSC_91533 | CAS_91533 | Dimethindene)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details
PubMed