BDBM8119 Hydroxyethylene Sulfone 17c::N-[(2S,3R,5S)-1-(3-bromophenyl)-7-(2,4-dichlorophenyl)-5-[(4-fluorobenzene)sulfonyl]-3-hydroxyheptan-2-yl]-2-(2,4-dichlorophenoxy)acetamide::N-{(1S,2R,4S)-1-(3-bromobenzyl)-6-(2,4-dichlorophenyl)-4-[(4-fluorophenyl)sulfonyl]-2-hydroxyhexyl}-2-(2,4-dichlorophenoxy)acetamide

SMILES O[C@H](C[C@H](CCc1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc(F)cc1)[C@H](Cc1cccc(Br)c1)NC(=O)COc1ccc(Cl)cc1Cl

InChI Key InChIKey=OFJXLSRGQHBJLB-UHFFFAOYSA-N

Data  1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8119   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8119(N-[(2S,3R,5S)-1-(3-bromophenyl)-7-(2,4-dichlorophe...)
Affinity DataKi:  7.00E+3nM ΔG°:  -7.03kcal/mole IC50: 1.00E+4nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2006
Entry Details Article
PubMed