BDBM809319 (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-trifluoroethoxy)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic Acid::US12643889, Compound I-33

SMILES C[C@H](NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(OCC(F)(F)F)c1)c1ccc(C(=O)O)cc1

InChI Key InChIKey=SABGTGWKGWUXAF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 809319   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809319BDBM809319((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-...)
Affinity DataKi:  17nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809319BDBM809319((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-...)
Affinity DataIC50: 31nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent